The following is a summary of acts which authorized boundary changes for Pickett County.
- Acts of 1885, Chapter 117, changed the boundary between Overton and Pickett Counties to include in Overton all of the tract of land belonging to John Hill known as his mountain tract, the McDonald tract, all of the tract of land belonging to A. C. Brown, all of fifty acre tract belonging to Conoway Cooper and all of Milton K. Hargrove's tract of land.
- Acts of 1885, Chapter 125, changed the line between the counties of Clay and Pickett to include in Clay county the farm known as the W. C. Heard farm and other lands or land owned by W. W. Heard and W. H. Wilburn. Also to include in Clay County all of the tract or tracts of land belonging to B. C. Wilburn and S. R. Heard.
- Acts of 1885, Chapter 156, changed the boundary between Fentress and Pickett to include within Fentress the whole of the lands of Stokley Crabtree, Marions Crouch and J. J. Pile lying in the head of Rotten Fork of Wolf River. Also to include in Fentress the lands of David Cooper, Jennie Cooper, Thos. King, Mary Ann Hoover, Geo. Smith, Austin Choate, Wm. Choate, Thos. Cooper, Wm. Cooper and Madison Hoover.
- Acts of 1887, Chapter 52, detached the lands of P. H. Wilburn from Pickett and placed them in Clay County.
- Acts of 1891, Chapter 28, changed the line between Fentress and Pickett Counties to include the farms of G. W. Crouch and Jackson Rains in the county of Pickett.
- Acts of 1891, Chapter 42, placed the farms of N. E. Storie and F. P. Storie in Pickett County.
- Acts of 1893, Chapter 57, changed the line between Pickett and Clay Counties along the Wolf and Obed Rivers, but this act was repealed by Acts of 1901, Chapter 270.
- Acts of 1897, Chapter 287, changed the line between Overton and Pickett Counties so as to include all of the farm of R. H. Smith in Overton County.
- Acts of 1899, Chapter 82, changed the boundary between Overton and Pickett to include the lands of James Conner in Overton County.
- Acts of 1899, Chapter 105, changed the line between Pickett and Fentress Counties so as to include all the lands of F. M. Lynch in Pickett.
- Acts of 1905, Chapter 39, changed the line between Pickett and Fentress to detach part of W. M. Johnson's land from Pickett and attach it to Fentress, at or near the Forbus Post office.
- Acts of 1905, Chapter 193, detached part of Lottie Sells' farm from Overton and placed it in Pickett County, near Spurier, Tennessee.
- Acts of 1905, Chapter 266, changed the line between the counties of Clay and Pickett to detach the land of Smith Mulens from Clay County and place it in Pickett, near Herd, Tennessee.
- Acts of 1905, Chapter 373, changed the line between Overton and Pickett Counties to place all of the lands of James Boles from Overton County and attach it to Pickett County, at or near Spurier, Tennessee.
- Acts of 1905, Chapter 378, changed the line between the counties of Overton and Pickett to remove another portion of Lottie Sells land from Overton County and place it in Pickett.
- Private Acts of 1911, Chapter 244, changed the line between Pickett and Fentress to include all the land of the Dry Creek farm owned by Robbins and Parris in Pickett County.
- Private Acts of 1915, Chapter 686, changed the county line between the counties of Pickett and Overton to include all the land of A. J. Lacy in Pickett County.
- Private Acts of 1921, Chapter 453, changed the boundary between Pickett and Fentress to detach the lands of Hiram C. Crabtree from Fentress and place them in Pickett.
- Private Acts of 1921, Chapter 700, changed the line between Fentress and Pickett to detach the Ed Storie farm from Fentress and place it in Pickett. 20. Private Acts of 1921, Chapter 803, changed the line between the counties of Pickett and Fentress to place the lands of E. G. Jones in the Ninth District of Pickett County.
- Private Acts of 1921, Chapter 804, changed the boundary between Pickett and Fentress to place the lands of S. R. West in the Ninth District of Pickett County.
- Private Acts of 1925, Chapter 700, placed all of the farm of Nona Crouch in Fentress County.
- Private Acts of 1933, Chapter 213, changed the line between Overton and Pickett Counties to include the farm of Herman Parrott in Pickett County.